PZM — Next Generation Sequencing Based Tumor Profiling Test Class II

FDA Device Classification

Classification Details

Product Code
PZM
Device Class
Class II
Regulation Number
866.6080
Submission Type
Review Panel
PA
Medical Specialty
Pathology
Implant
No

Definition

A next-generation sequencing based tumor profiling test is a qualitative in vitro diagnostic test intended to detect mutations in a broad panel of targeted genes that are somatically altered in malignant neoplasms from tumor specimens obtained from patients diagnosed with malignant solid neoplasms using targeted next-generation sequencing.

Recent 510(k) Clearances

K-NumberApplicantDevice NameDate
K241868tempus aixR IVDSeptember 19, 2025
K250003geneseeq technologyGENESEEQPRIME NGS Tumor Profiling Assay (FFPE) (GS6005)August 29, 2025
K210017act genomicsACTOnco, ACTOnco IVDDecember 23, 2022
K202304nyu langone medical centerNYU Langone Genome PACT (Genome Profiling of Actionable Cancer Targets)July 14, 2021
K192063personal genome diagnosticsPGDx elio tissue completeApril 24, 2020
K190661nanthealthOmics CoreNovember 9, 2019
DEN170058memorial sloan-kettering cancer centerMSK-IMPACT (Integrated Mutation Profiling of Actionable Cancer Targets):a HybridNovember 15, 2017