bupivacaine hydrochloride and epinephrine bitartrate

FDA Drug Profile — Marcaine, Vivacaine, MARCAINE WITH EPINEPHRINE

bupivacaine hydrochloride and epinephrine bitartrate is listed in the FDA National Drug Code directory with 3 NDC codes, marketed under brand names including Marcaine, Vivacaine, MARCAINE WITH EPINEPHRINE. Available dosage form: injection, solution.

Drug Details

Generic Name
bupivacaine hydrochloride and epinephrine bitartrate
Brand Names
Marcaine, Vivacaine, MARCAINE WITH EPINEPHRINE
Application Number
ANDA077250
Sponsor
Septodont, Inc.
NDC Codes
3
Dosage Forms
INJECTION, SOLUTION
Routes
SUBMUCOSAL, EPIDURAL, INFILTRATION, INTRACAUDAL, PERINEURAL
Active Ingredients
BUPIVACAINE HYDROCHLORIDE ANHYDROUS, EPINEPHRINE BITARTRATE, BUPIVACAINE HYDROCHLORIDE

Indications and Usage

1 INDICATIONS AND USAGE SENSORCAINE / SENSORCAINE WITH EPINEPHRINE is indicated in adults for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. Specific concentrations and presentations of SENSORCAINE / SENSORCAINE WITH EPINEPHRINE are recommended for each type of block indicated to produce local or regional anesthesia or analgesia [see Dosage and Administration ( 2.2 )]. SENSORCAINE contains bupivacaine, an amide local anesthetic, and SENSORCAINE WITH EPINEPHRINE is a combination of bupivacaine, an amide local anesthetic, and epinephrine, an alpha and beta-adrenergic agonist. SENSORCAINE/ SENSORCAINE WITH EPINEPHRINE is indicated in adults for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. For each type of block indicated to produce local or regional anesthesia or analgesia, specific concentrations and presentations are recommended. ( 1 , 2.2 ) Limitations of Use Not all blocks are indicated for use with SENSORCAINE/ SENSORCAINE WITH EPINEPHRINE given clinically significant risks associated with use. ( 1 , 2.2 , 4 , 5.1 , 5.4 , 5.5 , 5.7 , 5.9 ) Limitations of Use Not all blocks are indicated for use with SENSORCAINE / SENSORCAINE WITH EPINEPHRINE given clinically significant risks associated with use [see Dosage and Administration ( 2.2 ), Contraindications ( 4 ), Warnings and Precautions ( 5.1 , 5.4 , 5.5 , 5.7 , 5.9 )] .