Cladribine

FDA Drug Profile — Cladribine, Mavenclad

Drug Details

Generic Name
Cladribine
Brand Names
Cladribine, Mavenclad
Application Number
ANDA210856
Sponsor
Cilag AG
NDC Codes
15
Dosage Forms
POWDER, INJECTION, SOLUTION, INJECTION, TABLET
Routes
INTRAVENOUS, ORAL
Active Ingredients
CLADRIBINE

Indications and Usage

1 INDICATIONS AND USAGE Cladribine tablets are indicated for the treatment of relapsing form of multiple sclerosis (MS), to include relapsing-remitting disease in adults. Because of its safety profile, use of cladribine tablets is generally recommended for patients who have had an inadequate response to, or are unable to tolerate, an alternate drug indicated for the treatment of MS [ see Warnings and Precautions (5) ]. Limitations of Use Cladribine tablets are not recommended for use in patients with clinically isolated syndrome (CIS) because of its safety profile [ see Warnings and Precautions (5) ]. Cladribine tablets are purine antimetabolite indicated for the treatment of relapsing form of multiple sclerosis (MS), to include relapsing-remitting disease in adults. Because of its safety profile, use of cladribine tablets are generally recommended for patients who have had an inadequate response to, or are unable to tolerate, an alternate drug indicated for the treatment of MS. ( 1 , 5 ) Limitations of Use Cladribine tablets are not recommended for use in patients with clinically isolated syndrome (CIS) because of its safety profile. ( 1 , 5 )