cyclopentolate hydrochloride and phenylephrine hydrochloride

FDA Drug Profile — Cyclomydril

Drug Details

Generic Name
cyclopentolate hydrochloride and phenylephrine hydrochloride
Brand Names
Cyclomydril
Application Number
ANDA084300
Sponsor
Alcon Laboratories, Inc.
NDC Codes
1
Dosage Forms
SOLUTION/ DROPS
Routes
OPHTHALMIC
Active Ingredients
CYCLOPENTOLATE HYDROCHLORIDE, PHENYLEPHRINE HYDROCHLORIDE

Indications and Usage

INDICATIONS AND USAGE For the production of mydriasis.

Warnings

WARNINGS FOR TOPICAL OPHTHALMIC USE ONLY. NOT FOR INJECTION. There have been reports of serious cardiovascular reactions, including ventricular arrhythmias and myocardial infarctions, in patients using higher concentrations of phenylephrine. These episodes, some fatal, have usually occurred in patients with pre-existing cardiovascular diseases. This preparation may cause central nervous system (CNS) disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate.