Dexrazoxane

FDA Drug Profile — Dexrazoxane

Drug Details

Generic Name
Dexrazoxane
Brand Names
Dexrazoxane
Application Number
ANDA076068
Sponsor
MSN Laboratories Private Limited
NDC Codes
8
Dosage Forms
POWDER, INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Routes
INTRAVENOUS
Active Ingredients
DEXRAZOXANE, DEXRAZOXANE HYDROCHLORIDE

Indications and Usage

1 INDICATIONS AND USAGE Dexrazoxane for injection is indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose of 300 mg/m 2 and who will continue to receive doxorubicin therapy to maintain tumor control. Do not use with the initiation of doxorubicin therapy [see Warnings and Precautions (5.2) ] . Dexrazoxane for injection is a cytoprotective agent indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose of 300 mg/m 2 and who will continue to receive doxorubicin therapy to maintain tumor control. Do not use dexrazoxane for injection with doxorubicin initiation.