dornase alfa

FDA Drug Profile — Pulmozyme

Drug Details

Generic Name
dornase alfa
Brand Names
Pulmozyme
Application Number
BLA103532
Sponsor
Lonza Biologics Tuas Pte Ltd.
NDC Codes
3
Dosage Forms
LIQUID, SOLUTION
Routes
RESPIRATORY (INHALATION)
Active Ingredients
DORNASE ALFA

Indications and Usage

1 INDICATIONS AND USAGE PULMOZYME ® is indicated, in conjunction with standard therapies, for the management of pediatric and adult patients with cystic fibrosis (CF) to improve pulmonary function. In CF patients with an FVC ≥ 40% of predicted, daily administration of PULMOZYME has also been shown to reduce the risk of respiratory tract infections requiring parenteral antibiotics. PULMOZYME is a recombinant DNase enzyme indicated in conjunction with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function. ( 1 )