eladocagene exuparvovec-tneq

FDA Drug Profile — KEBILIDI

Drug Details

Generic Name
eladocagene exuparvovec-tneq
Brand Names
KEBILIDI
Application Number
BLA125722
Sponsor
PTC Therapeutics, Inc.
NDC Codes
1
Dosage Forms
SUSPENSION
Routes
INTRACEREBRAL
Active Ingredients
ELADOCAGENE EXUPARVOVEC

Indications and Usage

1 INDICATIONS AND USAGE KEBILIDI (eladocagene exuparvovec-tneq) is an adeno-associated virus (AAV) vector-based gene therapy indicated for the treatment of adult and pediatric patients with aromatic L-amino acid decarboxylase (AADC) deficiency. This indication is approved under accelerated approval based on the change from baseline in gross motor milestone achievement at 48 weeks post treatment [see Clinical Studies ( 14 )] . Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory clinical trial. KEBILIDI is an adeno-associated virus (AAV) vector-based gene therapy indicated for the treatment of adult and pediatric patients with aromatic L amino acid decarboxylase (AADC) deficiency. This indication is approved under accelerated approval based on change from baseline in gross motor milestone achievement at 48 weeks post-treatment. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory clinical trial. ( 1 , 14 )