irinotecan hydrochloride

FDA Drug Profile — Camptosar, Irinotecan Hydrochloride

irinotecan hydrochloride is listed in the FDA National Drug Code directory with 4 NDC codes, marketed under brand names including Camptosar, Irinotecan Hydrochloride. Available dosage form: injection, solution.

Drug Details

Generic Name
irinotecan hydrochloride
Brand Names
Camptosar, Irinotecan Hydrochloride
Application Number
NDA020571
Sponsor
Pharmacia & Upjohn Company LLC
NDC Codes
4
Dosage Forms
INJECTION, SOLUTION
Routes
INTRAVENOUS
Active Ingredients
IRINOTECAN HYDROCHLORIDE

Indications and Usage

1 INDICATIONS AND USAGE Irinotecan hydrochloride injection is indicated as a component of first-line therapy in combination with 5-fluorouracil (5-FU) and leucovorin (LV) for patients with metastatic carcinoma of the colon or rectum. Irinotecan hydrochloride injection is indicated for patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy. Irinotecan hydrochloride injection is a topoisomerase inhibitor indicated for: First-line therapy in combination with 5-fluorouracil and leucovorin for patients with metastatic carcinoma of the colon or rectum. ( 1 ) Patients with metastatic carcinoma of the colon or rectum whose disease has recurred or progressed following initial fluorouracil-based therapy. ( 1 )