linagliptin and metformin hydrochloride

FDA Drug Profile — Jentadueto, Jentadueto XR

linagliptin and metformin hydrochloride is listed in the FDA National Drug Code directory with 9 NDC codes, marketed under brand names including Jentadueto, Jentadueto XR. Available dosage forms: tablet, tablet, film coated, tablet, film coated, extended release.

Drug Details

Generic Name
linagliptin and metformin hydrochloride
Brand Names
Jentadueto, Jentadueto XR
Application Number
NDA201281
Sponsor
Boehringer Ingelheim Pharma GmbH and Co. KG
NDC Codes
9
Dosage Forms
TABLET, TABLET, FILM COATED, TABLET, FILM COATED, EXTENDED RELEASE
Routes
ORAL
Active Ingredients
METFORMIN HYDROCHLORIDE, LINAGLIPTIN

Indications and Usage

1 INDICATIONS AND USAGE JENTADUETO XR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus . JENTADUETO XR is a combination of linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor and metformin hydrochloride (HCl), a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus ( 1 ) Limitations of Use Not recommended in patients with type 1 diabetes mellitus ( 1 ) Has not been studied in patients with a history of pancreatitis ( 1 ) Limitations of Use JENTADUETO XR is not recommended in patients with type 1 diabetes mellitus. JENTADUETO XR has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at an increased risk for the development of pancreatitis while using JENTADUETO XR [see Warnings and Precautions (5.2) ].