pralatrexate

FDA Drug Profile — Folotyn

Drug Details

Generic Name
pralatrexate
Brand Names
Folotyn
Application Number
NDA022468
Sponsor
Acrotech Biopharma Inc
NDC Codes
2
Dosage Forms
INJECTION
Routes
INTRAVENOUS
Active Ingredients
PRALATREXATE

Indications and Usage

1 INDICATIONS AND USAGE Pralatrexate injection is indicated for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). This indication is approved under accelerated approval based on overall response rate [see Clinical Studies ( 14 )] . Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). Pralatrexate injection is a dihydrofolate reductase inhibitor indicated for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). This indication is approved under accelerated approval based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). ( 1 )