temozolomide

FDA Drug Profile — temozolomide, TEMOZOLOMIDE

Drug Details

Generic Name
temozolomide
Brand Names
temozolomide, TEMOZOLOMIDE
Application Number
ANDA213328
Sponsor
Nivagen Pharmaceuticals, Inc.
NDC Codes
14
Dosage Forms
CAPSULE, POWDER, INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Routes
ORAL
Active Ingredients
TEMOZOLOMIDE

Indications and Usage

1. INDICATIONS AND USAGE TEMOZOLOMIDE Capsules, USP are an alkylating drug indicated for the treatment of adult patients with: • Newly diagnosed glioblastoma concomitantly with radiotherapy and then as maintenance treatment. ( 1.1 ) • Refractory anaplastic astrocytoma who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine. ( 1.2 ) 1.1 Newly Diagnosed Glioblastoma TEMOZOLOMIDE Capsules, USP is indicated for the treatment of adult patients with newly diagnosed glioblastoma concomitantly with radiotherapy and then as maintenance treatment. 1.2 Refractory Anaplastic Astrocytoma TEMOZOLOMIDE Capsules , USP is indicated for the treatment of adult patients with refractory anaplastic astrocytoma who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine.