tiopronin

FDA Drug Profile — Thiola, Thiola EC, VENXXIVA, tiopronin, TIOPRONIN

Drug Details

Generic Name
tiopronin
Brand Names
Thiola, Thiola EC, VENXXIVA, tiopronin, TIOPRONIN
Application Number
NDA019569
Sponsor
Mission Pharmacal Company
NDC Codes
8
Dosage Forms
TABLET, SUGAR COATED, TABLET, DELAYED RELEASE
Routes
ORAL
Active Ingredients
TIOPRONIN

Indications and Usage

1 INDICATIONS AND USAGE VENXXIVA is indicated, in combination with high fluid intake, alkali, and diet modification, for the prevention of cystine stone formation in adults and pediatric patients 9 years of age and older with severe homozygous cystinuria, who are not responsive to these measures alone. Additional pediatric use information is approved for Mission Pharmacal Company’s Thiola EC (tiopronin delayed-release) tablets. However, due to Mission Pharmacal Company’s marketing exclusivity rights, this drug product is not labeled with that information. VENXXIVA is a reducing and complexing thiol indicated, in combination with high fluid intake, alkali, and diet modification, for the prevention of cystine stone formation in adults and pediatric patients 9 years of age and older with severe homozygous cystinuria, who are not responsive to these measures alone. ( 1 )