tobramycin

FDA Drug Profile — TOBREX, tobramycin, BETHKIS

Drug Details

Generic Name
tobramycin
Brand Names
TOBREX, tobramycin, BETHKIS
Application Number
NDA050555
Sponsor
Novartis Pharmaceuticals Corporation
NDC Codes
3
Dosage Forms
OINTMENT, INJECTION, POWDER, FOR SOLUTION, SOLUTION
Routes
OPHTHALMIC, INTRAVENOUS, RESPIRATORY (INHALATION)
Active Ingredients
TOBRAMYCIN

Indications and Usage

1 INDICATIONS AND USAGE Tobramycin inhalation solution is indicated for the management of cystic fibrosis in adults and pediatric patients 6 years of age and older with Pseudomonas aeruginosa . Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with forced expiratory volume in 1 second (FEV 1 ) <25% or >75% predicted, or patients colonized with Burkholderia cepacia [see Clinical Studies (14) ]. Tobramycin inhalation solution is an aminoglycoside antibacterial indicated for the management of cystic fibrosis in adults and pediatric patients 6 years of age and older with Pseudomonas aeruginosa. Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with forced expiratory volume in 1 second (FEV 1 ) <25% or >75% predicted, or patients colonized with Burkholderia cepacia .