trimethobenzamide hydrochloride

FDA Drug Profile — Tigan

Drug Details

Generic Name
trimethobenzamide hydrochloride
Brand Names
Tigan
Application Number
NDA017530
Sponsor
Par Health USA, LLC
NDC Codes
1
Dosage Forms
INJECTION
Routes
INTRAMUSCULAR
Active Ingredients
TRIMETHOBENZAMIDE HYDROCHLORIDE

Indications and Usage

1 INDICATIONS AND USAGE Trimethobenzamide hydrochloride capsules is indicated in adults for the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis. Limitation of Use: Trimethobenzamide hydrochloride capsules is not recommended for use in pediatric patients due to the risk of extrapyramidal signs and symptoms and other serious central nervous system (CNS) effects, and the risk of exacerbation of the underlying disease in pediatric patients with Reye's syndrome or other hepatic impairment. Trimethobenzamide hydrochloride capsules are an antiemetic indicated in adults for the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis. ( 1 ) Limitation of Use: • Trimethobenzamide hydrochloride capsules are not recommended for use in pediatric patients due to the risk of extrapyramidal signs and symptoms and other serious central nervous system (CNS) effects and the risk of exacerbation of the underlying disease in pediatric patients with Reye's syndrome or other hepatic impairment. ( 1 , 8.4 )