FDA Inspection 601990 — Truett Laboratories, Inc.

Truett Laboratories, Inc. — FEI 2018612

The FDA completed an inspection of Truett Laboratories, Inc. on July 6, 2009 in Azusa, CA. The inspection was classified OAI (Official Action Indicated — objectionable conditions were found and regulatory action is recommended). 40 citations were issued during this inspection. Product area: Drugs.

Inspection Details

Classification
Official Action Indicated (OAI) (OAI)
End Date
July 6, 2009
Fiscal Year
2009
Product Type
Drugs
Project Area
Drug Quality Assurance
Location
Azusa, CA (United States)

Citations

IDCFRDescription
108621 CFR 211.22(b)Adequate lab facilities not available
110521 CFR 211.22(d)Procedures not in writing, fully followed
125621 CFR 211.68(b)Backup file not maintained
126121 CFR 211.68(a)Written calibration / inspection records not kept
127421 CFR 211.68(a)Calibration/Inspection/Checking not done
129321 CFR 110.20(b)(2)Contamination with microorganisms, chemicals, filth, etc.
135821 CFR 211.100(b)SOPs not followed / documented
136121 CFR 211.100(a)Absence of Written Procedures
144821 CFR 211.111Establishment of time limitations
149521 CFR 211.122(a)Written procedures describing in detail
154021 CFR 211.125(a)Strict control not exercised over labeling issued
154121 CFR 211.125(b)Examination of issued labels
154521 CFR 211.125(c)Label reconciliation discrepancies evaluation/investigation
155021 CFR 211.125(f)Procedures Written and Followed
172821 CFR 211.87Retest of approved components/containers/closures
176721 CFR 211.137(a)Expiration date lacking
181021 CFR 211.160(a)Lab controls established, including changes
188521 CFR 211.165(b)Microbiological testing
189021 CFR 211.165(e)Test methods
192021 CFR 211.166(a)(3)Valid stability test methods
192721 CFR 211.166(b)Accelerated stability studies
200921 CFR 211.188Prepared for each batch, include complete information
202221 CFR 211.188(b)(10)Documentation of Sampling Performed
202721 CFR 211.192Investigations of discrepancies, failures
310321 CFR 820.30(i)Design changes - Lack of or Inadequate Procedures
344521 CFR 211.65(a)Equipment construction - reactive surfaces
355321 CFR 211.48(a)Plumbing System Defects
357121 CFR 211.100(a)Changes to Procedures Not Reviewed, Approved
357221 CFR 211.100(b)Procedure Deviations Recorded and Justified
358521 CFR 211.110(a)Control procedures to monitor and validate performance
360321 CFR 211.160(b)Scientifically sound laboratory controls
361321 CFR 211.160(b)(4)Establishment of calibration procedures
431421 CFR 211.84(d)(2)Reports of Analysis (Components)
431521 CFR 211.84(d)(2)Testing Each Component for Conformity with Specs
433021 CFR 211.130(e)Packaging line inspection documentation
435221 CFR 211.160(b)(4)Calibration - at intervals, written program, remedial action
435721 CFR 211.166(a)Results not used for expiration dates, storage cond.
436721 CFR 211.188(b)(13)Examinations for correct labeling
440021 CFR 211.186(b)(8)Description of containers, labels, et. al.
44721 CFR 820.40Lack of procedures, or not maintained