FDA Inspection 743307 — Dakota Laboratories, LLC

Dakota Laboratories, LLC — FEI 1721400

The FDA completed an inspection of Dakota Laboratories, LLC on August 31, 2011 in Mitchell, SD. The inspection was classified OAI (Official Action Indicated — objectionable conditions were found and regulatory action is recommended). 22 citations were issued during this inspection. Product area: Drugs.

Inspection Details

Classification
Official Action Indicated (OAI) (OAI)
End Date
August 31, 2011
Fiscal Year
2011
Product Type
Drugs
Project Area
Drug Quality Assurance
Location
Mitchell, SD (United States)

Citations

IDCFRDescription
103321 CFR 211.22(a)Authority lacking to review records, investigate errors
104921 CFR 211.22(a)Approve or reject components, products
110521 CFR 211.22(d)Procedures not in writing, fully followed
111121 CFR 211.25(a)Training , Education , Experience overall
119421 CFR 211.42(c)Defined areas of adequate size for operations
121521 CFR 211.67(b)Written procedures not established/followed
127421 CFR 211.68(a)Calibration/Inspection/Checking not done
145121 CFR 211.113(b)Procedures for sterile drug products
145221 CFR 211.113(b)Validation lacking for sterile drug products
178721 CFR 211.80(a)Procedures To Be in Writing
180921 CFR 211.160(a)Following/documenting laboratory controls
185121 CFR 211.84(e)Rejecting When Specifications Not Met
191421 CFR 211.166(a)Lack of written stability program
191821 CFR 211.166(a)(2)Stability sample storage conditions described
200921 CFR 211.188Prepared for each batch, include complete information
202721 CFR 211.192Investigations of discrepancies, failures
354721 CFR 211.46(b)Equipment for Environmental Control
360321 CFR 211.160(b)Scientifically sound laboratory controls
430321 CFR 211.67(b)Written procedures fail to include
431421 CFR 211.84(d)(2)Reports of Analysis (Components)
431521 CFR 211.84(d)(2)Testing Each Component for Conformity with Specs
439121 CFR 211.180(e)(2)Items to cover on annual reviews