FDA Inspection 831836 — New Direction Biosciences LLC

New Direction Biosciences LLC — FEI 3009842420

The FDA completed an inspection of New Direction Biosciences LLC on June 6, 2013 in New York, NY. The inspection was classified OAI (Official Action Indicated — objectionable conditions were found and regulatory action is recommended). 18 citations were issued during this inspection. Product area: Biologics.

Inspection Details

Classification
Official Action Indicated (OAI) (OAI)
End Date
June 6, 2013
Fiscal Year
2013
Product Type
Biologics
Project Area
Human Cellular, Tissue, and Gene Therapies
Location
New York, NY (United States)

Citations

IDCFRDescription
113421 CFR 211.25(b)Supervisor Training/Education/Experience
127421 CFR 211.68(a)Calibration/Inspection/Checking not done
135821 CFR 211.100(b)SOPs not followed / documented
136121 CFR 211.100(a)Absence of Written Procedures
145221 CFR 211.113(b)Validation lacking for sterile drug products
145421 CFR 211.115(a)Reprocessing procedures not written or followed
178721 CFR 211.80(a)Procedures To Be in Writing
180921 CFR 211.160(a)Following/documenting laboratory controls
181021 CFR 211.160(a)Lab controls established, including changes
188321 CFR 211.165(a)Testing and release for distribution
191421 CFR 211.166(a)Lack of written stability program
202621 CFR 211.192Quality control unit review of records
202721 CFR 211.192Investigations of discrepancies, failures
203121 CFR 211.194(a)Complete test data included in records
360221 CFR 211.160(a)Deviations from laboratory control requirements
435321 CFR 211.160(b)(4)Instruments, apparatus, et. al. not meeting specs
441321 CFR 211.194(a)(8)Second person sign off
9821 CFR 606.100(c)Thorough investigations