Clemastine Fumarate

FDA Drug Profile — Clemastine Fumarate, CLEMSZA

Clemastine Fumarate is listed in the FDA National Drug Code directory with 7 NDC codes, marketed under brand names including Clemastine Fumarate, CLEMSZA. Available dosage forms: powder, syrup, tablet.

Drug Details

Generic Name
Clemastine Fumarate
Brand Names
Clemastine Fumarate, CLEMSZA
Application Number
ANDA073399
Sponsor
STHREE CHEMICALS PRIVATE LIMITED
NDC Codes
7
Dosage Forms
POWDER, SYRUP, TABLET
Routes
ORAL
Active Ingredients
CLEMASTINE FUMARATE

Indications and Usage

INDICATIONS AND USAGE Clemastine Fumarate Syrup is indicated for the relief of symptoms associated with allergic rhinitis such as sneezing, rhinorrhea, pruritus and lacrimation. Clemastine Fumarate Syrup is indicated for use in pediatric populations (age 6 years through 12) and adults (see DOSAGE AND ADMINISTRATION ). It should be noted that clemastine is indicated for the relief of mild uncomplicated allergic skin manifestations of urticaria and angioedema at the 2 mg dosage level only.

Warnings

WARNINGS Antihistamines should be used with considerable caution in patients with: narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, symptomatic prostatic hypertrophy, and bladder neck obstruction. Use with CNS Depressants Clemastine has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc.). Use in Activities Requiring Mental Alertness Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc. Use in the Elderly (approximately 60 years or older) Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients.